期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

学习记忆相关基因研究进展

Advances in study on learning and memory related genes
下载PDF
导出
摘要 学习记忆是脑的重要功能之一,与学习记忆相关的基因很多,它们通过影响突触功能、信号转导、转录和翻译控制、能量代谢等途径进行学习记忆行为的调控。研究相关基因可为阐明学习记忆的分子机制和遗传机制奠定基础。 Learning and memory is one of important functions of brain.There are many genes related to learning and memory and they link closely with the function of neuron,signal transduction,factors of transcription and trans-lation,energy metabolism.These genes provide some data for revealing the molecular and genetic mechanism of learning and memory.
作者 程肖蕊 周文霞 张永祥
机构地区 军事医学科学院
出处 《生物技术通讯》 CAS 2003年第3期227-230,共4页 Letters in Biotechnology
关键词 学习记忆 基因 突触功能 信号转导 翻译控制 遗传机制 learning and memory gene
分类号 Q754 [生物学—分子生物学]
  • 相关文献

参考文献31

  • 1Routtenberg A, Cantallops I, Zaffuto S, et al. Enhanced learning after genetic overexpression of a brain growth protein[J]. Psychology, 2000,97(13):7657.
  • 2Masliah E, Rockenstein E, Veinbergs I, et al. β-Amyloid peptides enhance α-synuelein accumulation and neuronal deficits in atransgenic mouse model linking Alzheimer's disease and Parkinson's disease [J].Neurobiology, 2001,98(21):12245.
  • 3Nicoll RA, Malenka RC.Expression mechanisms underlying NMDA receptor-dependent long-term potentiation[J]. Ann NY Acad Sci, 1999,868:515.
  • 4Hong Bi, Chun-I Sze. N-methyl-D-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease[J]. J Neurol Sci, 2002,200:11.
  • 5Eiji S, Tang YP, Rampon C, et al. NMDA receptor-dependent synaptic reinforcement as a crucial process for memory consolidation[J]. Science,2000,290(10):1170.
  • 6Tang YP, Eiji S, Gilles RD, et al. Genetic enhancement of learning and memory in mice[J]. Nature, 1999,401:63.
  • 7Migaud M, Charlesworth P, Dempster M, et al. Enhanced long-term potentiation and impaired learning in mice with mutant postzynaptic density-95 protein[J]. Nature, 1998,396:433.
  • 8Calabresi P, Saiardi A, Pisani A, et al. Abnormal synaptic plasticity in the striatum of mice lacking dopamine D2 receptors[J].J Neurosci, 1997,17:4536.
  • 9Kim JJ, Shih JC, Chen K, et al. Selective enhancement of emotional, but not motor, learning in monoamine oxidase A--defleient mice[J]. Proc Nail Aead Sci LISA, 1997,94:5929.
  • 10Brunner HG, Nelen M, Breakefield XO, et al. Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A[J]. Science, 1993,262:578.
生物技术通讯
2003年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部