用脉冲辐解法研究尼古丁的化学活性

Study on the Chemical Activity of Nicotine by Pulse Radiolysis

首次运用电子脉冲辐解技术研究尼古丁分子的化学活性。实验表明 ,在尼古丁分子中存在有多个活性点 ,它们可分别与水合电子、氢自由基、羟基自由基作用 ,生成不同的中间产物 ,得到不同的吸收峰 ,并测定了它们的生成反应速率常数。尼古丁分子易与水合电子、氢自由基、羟基自由基作用这些特性可以解释尼古丁分子所具有的一些生理活性 ,同时为尼古丁分子的改性工作提供理论基础。

Nicotine has been studied for the first time by pulse radiolysis techniques. It has been found that hydrated electron, hydrogen radical, and hydroxyl radical can react on nicotine to produce an anion radical and neutral radical, respectively. Different absorption spectra were obtained, and the related rate constants were determined. The results provide some advices for scientists to study the harmfulness of smoking nicotine to people, which can give some new ideas to make harmless tobacco.