大鼠脑组织衰老超微结构变化研究

Ultrastructure changes of aging brain in rats

目的 研究老化大鼠脑皮层超微结构改变特征。方法 将 33月龄正常老年大鼠脑超薄切片 ,投射电镜观察。结果和结论 观察结果显示正常老龄大鼠脑有 3个特征性病理改变 :广泛的空泡化 ,特殊的病理小体 。

Objective To observe characteristic changes under electron microscope. Methods Brain tissues were taken from 33 month old normal Wistar rats. The ultrastructures were observed under an electron microscope. Results and conclusion Three characteristic changes are shown: extensive vacuolation, characteristic pathologic body and disappearance of synapse.