儿童血清抗氧化维生素水平及其干预研究

Levels of Antioxidant Vitamins in Serum of Children and Interventions

目的 了解不同营养状态儿童维生素摄入情况、血清抗氧化维生素水平及其干预效果。方法 对北京市 2 94名 7～ 1 1岁儿童 (其中肥胖 1 57名、超重 68名、体重正常 69名 )进行了 3d记录法调查膳食维生素摄入情况、血清维生素 (α -生育酚、β -胡萝卜素及维生素A、维生素C)水平 ,并进行 6个月的维生素E、C合剂 (每日维生素E 1 0mg ,维生素C 80mg)干预。结果 随肥胖度增加 ,血清维生素A上升、α -生育酚下降 ,差异无显著性 (P >0 .0 5) ;β -胡萝卜素下降 ,差异有显著性 (P <0 .0 5)。肥胖儿童维生素E摄入低于体重正常儿童 ,但差异无显著性 (P >0 .0 5)。服用维生素E、C合剂 6个月 ,血清α -生育酚、维生素C水平升高。结论 肥胖儿童血清抗氧化维生素水平低于体重正常儿童 ,服用日常供给量维生素E、C 。

Objective To identify the intakes of vitamins, the levels of serum anti-oxidation vitamins in children with different nutrition states and the effectiveness of interventions. Methods The intakes of vitamins were investigated with the 3-day record method and the levels of serum vitamins(α-tocopherol, β-carotene, vitamin A and vitamin C) were determined in 294 children aged 7-11 years including 157 obese, 68 overweight and 69 normal-weight children in Beijing. Then a 6-month intervention was implemented with vitamin E and vitamin C complex (taking 10mg of vitamin E and 80mg of vitamin C daily). Results The level of vitamin A increased, while those of α-tocopherol, β-carotene decreased along with obesity degree. However, only the change in serum β-carotene was statistically significant ( P <0.05). The intake of Vitamin E in obese children was slightly lower than that in normal-weight children, but without significant difference ( P <0.05). The levels of serum α-tocopherol and vitamin C increased after intervention. Conclusions Obese children had lower levels of serum antioxidant vitamins than normal-weight children, taking the daily recommended amounts of vitamin E and vitamin C in the form of supplements can raise the levels of serumα-tocopherol and vitamin C.