肺癌及其转移患者微观血瘀证的临床研究

Clinical Research on Micro - blood Stasis of Patients with Lung Cancer and Its Metastasis

目的:阐明肺癌及其转移与微观血瘀证的关系。方法:检测77例原发性肺癌患者血液流变学的指标,其中肺癌组(未转移者)50例,转移组27例和健康人对照组20例,并按中医辨证标准予以分型。结果:肺癌患者的多项指标较正常人差异有显著性(P<0.01或P<0.05);肺癌转移患者的血浆黏度、纤维蛋白原较肺癌未转移患者差异有显著性(P<0.05)。结论:肺癌患者血液处于高凝状态,对肺癌转移起重要作用,并表明肺癌及其转移患者存在着微观血瘀证,为活血化瘀法治疗肿瘤及其转移提供了理论依据。

Objective: to expound the relation between lung cancer and its metastasis and micro - blood stasis. Methods; the hemarheology index of 77 patients with primary lung cancer was examined, among whom cancer group consisted of 50 patients, metastasis group 27 patients and control group 20 patients, classified according to TCM dialectical Standard. Results: the differ-ence of the indexes between the patients of lung cancer and the normai is significant ( P < 0.01 or P < 0.05); the plasma viscosity and fibrinogen of the metastasis patients are great different from those of non metastasis patients ( P < 0. 05) . Conclusions: lung cancer patients have high congealed blood which affects the cancerometastasis and suggests that micro - blood stasis exists in both patients, which provides theoretical basis for treating tumor and its metastasis by blood -activating and stasis - dissolving method.