肝动脉化疗栓塞联合无水乙醇注射治疗中晚期肝癌的疗效观察

The Therapeutic Effect of Transcatheter Arterial Chemoembolization Combined with Percutaneous Ethanol Injection for Large Hepatocellular Carcinoma

目的 :探讨肝动脉化疗栓塞术 (TAE)联合 B超引导下经皮乙醇注射 (PEI)治疗中晚期肝癌的临床价值。方法 :6 5例应用 TAE+PEI治疗 ,6 8例单纯应用 TAE治疗 ,比较两组患者治疗后的肿瘤大小、甲胎蛋白 (AFP)的下降情况及生存率。结果 :联合组肿瘤缩小明显 ,AFP复常率高于 TAE组 ,而术后不良反应及肝功能损害较轻 ,患者的生存期延长。结论 :TAE+PEI联合治疗中晚期肝癌优于单纯 TAE。

Objective:To study the therapeutic effect of transcatheter arterial chemoembolization(TAE) combined with percutaneous ethanol injection(PEI) for large hepatocellular carcinoma(HCC).Methods:65 patients were treated with TAE and followed by PEI,whereas 68 patients received TAE alone.The following parameters:hepatocellular carcinoma size,AFP normalization and survival rate were evaluated.Results:The rate of tumor minification and AFP normalization in the TAE & PEI group was higher than that in the TAE alone group.The side effects and the liver damage were mild in the two group.The survival time of the patients in the TAE & PEI group was longer than that in the TAE alone group.Conclusion:The therapeutic effect of TAE combined with PEI is much better than that of TAE alone.