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新型葡激酶的研究进展 被引量:3

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摘要 本文详细阐述了新型葡激酶的结构、作用机理和改构现状。葡激酶是一种溶栓剂 ,具有纤维蛋白选择性好、溶栓效率高、价格经济等优点 ,但作为细菌源蛋白质 ,葡激酶用于患者会产生中和性抗体 ,严重影响它的治疗效果和反复应用。目前对葡激酶的研究主要致力于结构改造 ,减小其免疫原性 ,提高疗效。
出处 《解放军药学学报》 CAS 2003年第3期209-212,共4页 Pharmaceutical Journal of Chinese People's Liberation Army
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