摘要
以质量分数 5 0 %乙醛酸水溶液和原甲酸三甲酯为主要原料 ,经浓硫酸催化 ,合成二甲氧基乙酸甲酯。在考察了合成工艺条件的基础上 ,通过正交实验设计对该反应条件进行了优化 ,得到了最佳反应条件。二甲氧基乙酸甲酯的收率可达 92 .1 6 % .
A new process has been developed to synthesize dimethoxyacetic acid methyl ester from 50% solution of glyoxylic acid and methyl orthoformate through catalyzing by concentrated sulfuric acid.On the basis of observing and studying synthetic process conditions, the reaction conditions have been optimized by orthogonal experimental design , the production rate was up to 92.16% of dimethoxyacetic acid methyl ester.
出处
《太原理工大学学报》
CAS
2003年第4期447-448,451,共3页
Journal of Taiyuan University of Technology
关键词
乙醛酸
原甲酸三甲酯
正交设计
二甲氧基乙酸甲酯
glyoxylic acid
methyl orthoformate
orthogonal design
dimethoxyacetic acid methyl ester
