摘要
干扰素在治疗各类乙型肝炎中具有明确的疗效,是公认的抗病毒药物。它的治疗作用不仅在于抑制病毒蛋白复制,调节免疫紊乱,且可抑制肝脏纤维化,对肝炎后肝硬化发挥治疗作用。同时作者注意到,乙肝后肝硬化发病机理中涉及问题较广,单用干扰素治疗疗效受到一定限制,联合用药是提高疗效较好途径。
The treatment value of interferon and its combination with other drugs werevevaluated in cirrhosis following hepatitis B.The 113 patients were divided into five groups:①Interferon (56);②Interferon with 6 injectio aminoacipi(26);③Interferonv with Danshe Zhusheye or with injectio Vinorutoni(20);④6 Injectio Aminoacipi(36)and;Calf Ihympc peptid(25). The results showed that in Groups 2 and 3,the symptom and sign were improved better than Group(P<(0.05)or Groups 4 and 5(P<0.05).In serological aspect(HBsAg and HBeAg), the effect was better in GsouDs2 and3 than in Gro 1.
关键词
干扰素
肝硬变
乙型肝炎
:hepatitis
HBsAg
HBeAg
a-interferon
