陕西省2000～2001年分离鼠疫菌株特性及分析

Identification and analysis of the biological characteristics of Y. pestis strains isolated from Shaanxi Province 2000 to 2001

目的 为了解陕西省动物鼠疫流行的病原特点。方法 对2000～2001年定边县分离于不同宿主、媒介动物的19株鼠疫菌进行了生化、毒力因子和毒力测定。结果 所有菌株生化特点一致,4种毒力因子除1株菌为Pgm±外,均齐备。对5株菌的毒力测定LD_(50)介于41～180之间。结论 分离菌株为鄂尔多斯高原生态型强毒鼠疫菌。

Objective To understand the features of Pathogens caused plague epizootic in Shaanxi Province. Methods 19 Y. pestis strains isolated from variant host animals and vector insects in Dingbian County 2000 to 2001 were Identified biochemical characteristics, virulent factors and virulence to mouse. Results Through the test, all the strains had the same biochemical characteristics. Simultaneously all except one had the 4 virulent factors . Only one was Pgm±. 5 strains' Virulence tests showed the value of LD50 to mouse lay between 41 to 180. Conclusion All the strains belonged to Erdos Plateau ecotype, having high virulence.