高氟区改水后不同年限儿童尿氟水平动态观察

Dynamic observation on children urinary fluoride level in water - improving fluorosis region at different number of years

目的 观察研究高氟区改水后儿童尿氟水平动态,探讨降氟后不同病区、不同年限氟中毒的防治效果。方法 对轻、中、重病区改水1、3、5、7、9年各抽取2个病村(共30个村),每村8～12岁儿童随机抽取10例测定晨尿氟。结果 饮用低氟水的年限越长,尿氟水平越低。轻、中病区较重病区下降明显,改水后不同年龄儿童尿氟均值差异不大,但个体间差异较大。总体尿氟均值已由改水前的5.28 mg/L下降到1.91 mg/L,差异显著。结论 改饮低氟水后机体摄氟减少,亦反映了改水降氟防治氟中毒的效果。儿童尿氟可作为防治氟中毒效果考核的客观指标。

Objective To study the prophylactic - theraputic effct on fluorosis group after water - improved at different number of years and in different fluorosis region, through dynamic observing the change of children urinary fluoride concentration. Methods Select total 30 villages in fluorosis region as study object. Every two villages were from the same fluorosis region and at the same number of years after water improved. There were ten children from 8 to 12 years old random sampling from every village. Results The longer people had drunk the low - fluoride - water, the lower urinary fluoride level was. It was more obvious in mild and moderate fluorosis regions compared with severe fluorosis regions. The difference of average urinary fluoride had no significance between children in different age group, but individual differences were significant. The total average urinary fluoride has dropped to 1. 91 mg/L from 5. 28 mg/L after water had been improved. Conclusion The body absorbed less fluoride after water had been improved. It proved that there are obvious effect of prophylactic - therapeutic on fluorosis by improving water quality. Children urinary fluoride can be considered an objective index evaluating the effect of prophylactic - therapeutic fluorosis.