肝源性溃疡的临床观察

Clinical resarch on peptic ulcer resulted from liver disease

目的 :研究乙肝后肝硬化患者消化性溃疡的临床特点及治疗转归 ,探讨内镜下止血及小剂量心得安对肝源性溃疡愈合的影响。方法 :肝源性溃疡 75例 ,观察其发病年龄、临床表现、溃疡部位、HP感染率、出血率及 7d内止血率及溃疡愈合率等特点 ,随机分为治疗组 37例 ,内镜下止血 +心得安 +泰胃美治疗 ,对照组 38例 ,用维生素B6 +泰胃美治疗 ;另外选单纯性消化性溃疡 73例 ,随机对照2组 36例 ,用维生素B6 +泰胃美治疗 ,对照 3组 37例 ,内镜下止血 +维生素B6 +泰胃美治疗。结果 :肝源性溃疡发病年龄较单纯性消化性溃疡晚 1 0年 ,溃疡部位以复合性溃疡居多和并出血率高 ,内镜下止血 +小剂量心得安可明显提高肝源性溃疡 7d内止血率 ,促进肝源性溃疡愈合率 ,与对照组具有统计学意义 (P <0 .0 1 )。结论 :肝源性溃疡难以治愈且易并出血 ,且以复合性溃疡多见 ,门静脉高压因素可能从中发挥作用 ,内镜下注射及喷洒止血剂及口服小剂量心得安及用制酸护肝治疗能有效止血 。

Objective: To study the clinical feature and result of peptic ulcer in hepatic patients.Method: 75 patients whose peptic ulcer resulted form liver disease were divided into treating group (37 cases: gastroenterology + Xindeam + tagament) and control group (38 cases: V B6 +tagament). All of them were sudied on the age clinical symptoms peptic ulcer art. HP infection, rate hemorrhage rate and peptic ulcer cure rate. The other 73 cases with only peptic ulcer were divided into control 2 group( 36 cases: V B6 + tagamet). Control 3 group (37 cases: Gastroenterology + V B6 + tagamet). Result: Compare with the control grop. There's significance in stastic in peptic ulcer resulted from liver the age were later for 10 years, compound peptic ulcer and with high hemorrhage rate.Conclusion: It's difficult to treat peptic ulcer from hepatic disease and most of them with compound peptic ulcer. Xindean is effective on the curing of ulcer.