580例梅毒患者实验室检测结果分析

Serological analysis of 580 cases of syphilis

目的 对 5 80例梅毒患者的实验室检测结果进行了回顾分析 ,探讨梅毒血清学试验对梅毒各期患者的诊断评价。方法 采用梅毒非特异性抗体检测快速血浆反应素环状卡片试验 (RPR)和梅毒特异性抗体检测梅毒螺旋体明胶凝集试验 (TPPA) ,对 5 80例早期梅毒患者进行血清学检测 ,并采用RPR追踪观察驱梅药物的疗效。结果 Ⅰ期梅毒患者血RPR滴度为 1∶4者最多 6 2例 (2 3.6 % ) ,Ⅱ期梅毒患者血RPR滴度为 1∶32者最多 77例 (31.0 % ) ,潜伏梅毒患者血RPR滴度为 1∶16者最多 13例 (33.3% )。 5 80例梅毒患者TPPA检测均为阳性。结论 TPPA及RPR实验对于梅毒的诊断具有重要参考意义。

Objective To explore the significance of serological analysis from 580 syphilis patients by retrospective studies.Methods TPPA and RPR were conducted to determine syphilis virus. Results The number of the patients with the RPR titer 1:4 is the highest among primary syphilis cases , accounting for 23.6%,and among the secondary syphilis is 1:32, 31.0%.the number of patients with RPR titer 1:32 is the highest among the secondary syphilis cases, 77cases(31.0%),1:4 the least 26 cases(10.5%).Conclusion TPPA and RPR are of great significance for the diagnosis of syphilis. TPPA has very high sensitivity and specificity. It can be first selected clinical method to diagnostic Syphilis.