C反应蛋白与急性冠脉综合征的临床研究

The clinical study of the changes of C-reactive protein level in patients with acute coronary syndrome

目的 探讨C反应蛋白 (CRP)与急性冠脉综合症 (ACS)的关系。方法 测定ACS患者 4 0例 (其中不稳定型心绞痛患者组 2 3例 ,急性心肌梗死组 17例 )以及 2 0例非冠心病对照者血清CRP浓度。结果 与对照组相比 ,急性冠脉综合症各组CRP水平无显著性增高。不稳定型心绞痛组与急性心肌梗死组 (包括非ST段抬高心肌梗死 )CRP浓度也无显著性差异。结论 急性冠脉综合症与血清CRP水平关系不甚密切。CRP浓度可能不适合作为急性冠脉综合症的监测指标。

Objective To explore the relation between C reactive protein (CRP) concentration and existence of acute coronary syndrome (ACS). Methods CRP concentrations were measured in 40 patients with Coronary heart disease (CHD) (23 patients in the unstable angina group, 17 patients in the acute myocardial infarction group) and compared with those of 20 cases as normal control group (CHD was absent in this group). Results CRP concentration in patients with the two sorts of ACS was not significantly higher than that in normal control group and there was not a significant positive relation between the unstable angina group and acute myocardial infarction group about CRP level. Conclusion CRP concentration might not be used as an index for evaluating the existence of acute coronary syndrome.