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前列腺癌层粘蛋白表达与其浸润、转移相关性的研究 被引量:5

Analysis of the relationship between laminin expression and invasion,metastasis of prostatic cancer
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摘要 目的 探讨前列腺癌 (Pca)层粘蛋白 (LN)表达与其浸润、转移性的相互关系。方法 对 5 1例临床确定的Pca标本进行LN免疫组化标记 ,观察和描记其表达强度、分布和形态 ,结合临床生物学行为加以分析。结果 Pca细胞内LN的表达差异存在于癌细胞不同分化程度间 ,而细胞外基质LN的表达差异主要表现在浸润和转移性方面 ,均有显著的统计学意义。结论 Pca细胞内外LN的异质性表达 ,一定程度上反映了癌细胞分化程度和其浸润、转移的能力。
出处 《江苏医药》 CAS CSCD 北大核心 2003年第6期437-439,共3页 Jiangsu Medical Journal
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