喜炎平和利巴韦林治疗急性上呼吸道感染的比较

Observation of Effects of Xiyanping and Ribavirin on Acute Upper Respiratory Tract Infection

目的 比较喜类平注射液(主要成份:穿心莲内酯)和利巴韦林注射液治疗急性上呼吸道感染的临床疗效。方法 将204例急性上呼吸道感染患儿随机分成两组,治疗组133例,给予喜炎平注射液0.2～0.4m/(kg·d)。对照组71例,给予利巴韦林注射液10～15mg/(kg·d),两组均加苯唑青霉素50mg/kg·d,静滴。结果 治疗组治愈时间5.14±1.50d,对照组5.55±1.46d,两组平均治愈时间无显著差异(P>0.05),但治疗组平均退热时间与对照组比较有显著差异(P<0.05)。结论 喜炎平注射液具有抗病毒,抗菌作用,副作用小,是治疗小儿急性上呼吸道感染较理想的药物。

Objective To contrast medicinal effect of Xiyanping injection with that of ribavirin injection on acute upper respiratory tract infection. Methods 204 cases with acute upper respiratory tract infection were randomly divided into two groups. Treatment group were treated with Xiyanping injection 0. 2 - 0. 4ml/(kg. d) and oxacillin 25mg/(kg, d) ,i. v. gtt and control group with ribavirin injection 10~15mg/(kg. d) and oxacillin 25mg/ (kg. d),i. v. gtt. Results The time for recover in Xiyanping group is 5. 14±1. 50days;in control group is 5. 55± 1. 46 days. There is no difference ( P >0. 05). Conclusions Xiyanping injection have functions to resist both virus and gems. We suggest that to treat acute upper respiratory tract infection of children we would better select Xiyanping injection.