肺穿刺活检和血液抗体检测诊断菌阴肺结核

Studies of Diagnostic Values in Smear and Culture Negative Pulmonary Tuberculosis by Pathologic Examination and Detection of Antibody in Serum

目的 探讨不同方法联合检测对菌阴肺结核的诊断价值。方法 采用经皮肺穿刺活检组织标本进行病理诊断及不同方法血中结核抗体检测。结果 56例菌阴肺结核病人术前肺穿活检组织病理诊断阳性率为76.8％,不同方法血中结核抗体检测阳性率为57.1％,两项联合检测阳性率达92.9％。结论 两种方法联合检测菌阴肺结核敏感性、特异性高,具有广泛的推广应用价值。

Objective To investigate the diagnostic value of smear and culture negative pulmonary tuberculosis by combining different methods. Methods The specimens obtained from CT guided percutaneous fine needle lung biopsy was pathologic diagnosis and TB-AB in serum was detected using different methods before operation. Results The positive rate through pathologic diagnosis in 56 cases was 76. 8% ; Antibody positive in serum was 57. 1%. If combine both methods,the positive rate was 92. 9%. Conclusion The sensitivity and specificity diagnosis were higher by combining pathologic diagnosis and the detection of antibody in serum and the positive rate was increased. It is valuable for widely use in the diagnosis of smear and culture negative pulmonary tuberculosis by combining both methods.