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粘弹性肠道能动性模型的建立与数值模拟 被引量:6

AN ANALYSIS OF THE PERISTALTIC REFLEX WITH GASTROINTESTINAL ELASTICITY AND STICKINESS
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摘要 潜入人体肠道释放药物和进行手术的医用微型机器人的研究是目前的一个研究热点 ,人体肠道的能动性模型对于机器人的控制甚为重要。在理论分析和动物肠道力学特性实验结果的基础上建立了肠道的能动性模型 ,与粘性蠕动模型相比 ,能动性模型考虑肠道的弹性性质和粘性性质 ,更符合肠道的实际特性。与肠道中的液体方程耦合 ,利用神经控制模型的机械运动模型 ,运用Galerkin有限元 有限差分法进行了肠道的运动学仿真。 Gastrointestinal motility is responsible not only for mixing and transport of digester and elimination of undigested residues, but for the possibility and realization of microrobot entering the animal or human body for medical use. A mathematical model describing the dynamics of the peristaltic reflex considering gastrointestinal elasticity and stickiness is presented. Comparing with the peristaltic model only considering gastrointesinal stickiness, the model in this article is more appreciated to the intestinal motility. To solve the model, the Galerkin Finite Elements Method and the Finite Difference Method were used together. This mathematical model can be used for the controll of microrobot entering the animal or human body.
出处 《中国生物医学工程学报》 EI CAS CSCD 北大核心 2003年第3期267-273,共7页 Chinese Journal of Biomedical Engineering
基金 国家自然科学基金资助项目 (5 980 5 0 17) 国家"863"计划 (863 5 12 980 5 0 8)
关键词 肠道模型 医用微型机器人 蠕动边界 有限元-有限差分 Elasticity Finite difference method Finite element method Mathematical models Robots
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