摘要
目的 评估球囊成形术或支架置入治疗肾血管性高血压的安全性和疗效。方法 对 2 1例患者共 2 7条肾动脉狭窄 ,应用单纯高压球囊扩张或置入球囊扩张支架治疗。结果 2 7条病变动脉 ,2 0条扩张满意 ,7条狭窄肾动脉预扩张支架置入后 ,1例病变残余狭窄 11% ,其余 6条无残余狭窄。 2 1例患者血压均有明显下降 ,收缩压从 172± 11mmHg降至 12 6± 8mmHg ;舒张压从 115± 7mmHg降至 79± 6mmHg。 15例停用降压药血压仍正常。另 6例降压药从 4种减至 1种 ,血压仍能满意控制。结论 肾动脉扩张或支架置入是治疗肾血管性高血压简便、安全。
Objective To evaluate the safety and effecacy of renal angioplasty or stent placement in patients with poorly controlled hypertension caused by renal artery stenosis.Methods Twenty one patients,9 man and 12 women,aged 16~58 yems(42±18.2),suffered from severe renal artery stenosis.Balloon expan dable stents were placed in 7 arteries(diameter reduction 80%~100%),who had not been satisfactorily treated by high pressure balloon angio plasty.Results Renal angioplasty was sucess in twenty artery lesions.Angiographic sucess(remained stenosis 11% in 1 lesion and 0% in 6 lesions) was obtained in 7 artery lesions.Early clinical improvemint was seen in all patients.Their mean systolic blood pressure was reduced from 172±11mmHg to 126±8mmHg;the diastolis blood pessure from 115±7mmHg to 79±6mmHg.15 of 21 patients who discontinued to take anti hypertensive medications maintained their blood pressure at normal level,while other 6 patients reduced dosage of the anti hypertensive medications from 4 kind to 1 still controlled their blood pressure satisfactorily.Conclusion In this study the renal angioplasy and renal artery stenting appear to be an effective and safe mean for renovascular hypertension.