2002年度我院151例抗感染药ADR报告分析

Analysis on our Hospital's Reports of Adverse Drug Reactions on Anti-infectives in 2002

目的 了解我院抗感染药物发生的ADR情况及其给患者造成的危害。方法 对我院 2 0 0 2年度 15 1例ADR病例报告进行分类统计和分析评价。结果 涉及ADR的药物共有 31个品种 ,其中以喹诺酮类居首位 ,其次为头孢菌素类。合并用药占 5 8 3% ,用药途径以静脉注射为主。主要的ADR类型为皮肤损害 ,其次是胃肠系统损害。重度ADR13例 (8 6 % )。结论 应继续加强抗感染药物ADR监测 ,尤其加强不易观察的不良反应及慢性ADR的监测。

Objective To make clear the development of adverse drug reactions of anti-infectives and their damage to patients in our hospital.Methods Our hospital's 151 cases of reports on anti-infectives in 2002 were classified,analysed and evaluated.Results 31 kinds of drug developed adverse drug reactions, and the occurrence of combined use of drugs was 58.3%.The dosages given intraveneously were the majority.The main types of ADRs were skin damages, and next were gastro-intestinal damages. In 13 cases serious ADRs(8.6%) were caused.Conclusion The adverse drug reactions difficult to be observed and to be chronic should be paid more attention.