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影响输精管吻合后生育力恢复相关因素的初探 被引量:7

A limitary study on factors of fertility recovery after vasovasostomy
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摘要 目的 探讨影响输精管吻合术后生育力恢复的相关因素。方法  4 1例对象 ,在输精管吻合术时 ,收集30例近睾端输精管液体 (附睾精子 ) ,在输精管吻合术后 3~ 18个月进行精液和妊娠的随访。分别做了多种参数的分析。统计有关参数之间的关系 ,并用Logistic回归对术后生育恢复与上述参数的关系进行分析。结果 按术后是否使妻子怀孕分为生育组 (2 0例 )和未育组 (2 1例 )。两组除输精管结扎术后的年限在未育组显著高于生育组外 ,附睾精子分析的结果均无差异。输精管吻合术后精液分析的结果显示 :除精子活动率、精子存活率、正常形态精子等在未育组显著低于生育组外 ,其它均无显著差别。Logistic回归分析结果表明 :输精管吻合术后生育力恢复与精子活动率和正常形态精子两个变量有关。结论 输精管吻合术后精液中精子活动率、精子存活率、正常形态精子未能恢复至正常水平 ,是影响输精管吻合术后未能生育的因素。 Objective To analyze the factors of fertility recovery after vasovasostomy.Methods 41 operations of vasectomy reversal were performed.Semen analysis and pregnancy determination were followed up at 3~18 mouths after vasovsostomy.Of them the fluids of proximal vas deferens(FPVD,including epididmal spermatozoa) were also collected from 30 men.The sperm parameters in semen and FPVD,were performed.The relationship between the sperm parameters and pregnancy was analyzed using Logistic Regression programme.Results There was no significant difference between fertile(19 cases) group and infertile(11 cases) group in epididymal sperm parameters except the time between vasovaso stomy and vasectomy.The percentage of sperm motility,sperm viability and normal sperm morphology in semen of infertile group(21 cases) was significantly lower than that of fertile group(20 cases).The results of Logistic Regression analysis showed that there was a significant relationship between the percentage of sperm motility,normal sperm morphology and fertility recovery after vasovasostomy.Conclusions The factors of affecting fertility recovery after vasovasostomy were lower sperm motility and poor sperm morphology in the semen.
出处 《中国男科学杂志》 CAS CSCD 2003年第3期184-187,共4页 Chinese Journal of Andrology
基金 国家计划生育委员会课题 ( 910 2 3 )
关键词 精液 附睾精子 输精管结扎术 输精管吻合术 semen epididymal spermatozoa vasectomy vasectomy reversal
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