血清CA_(125)和PRL测定对子宫腺肌病的诊断价值

The Diagnostic Significance of Serum CA_(125) and PRL for the Patients with Adenomyosis of Uterus

目的 探讨血清CA1 2 5和泌乳素 (Prolactin ,PRL)测定对子宫腺肌病 (AD)的诊断价值。方法 应用酶免测定法及电化学发光法分别测定AD患者 (AD组 )和非AD患者 (NAD组 )的血清CA1 2 5和PRL水平。结果 AD组的血清CA1 2 5和PRL水平分别为 5 8 91± 5 42kU/L和 3 1 0 1± 5 3 7μg/L ,阳性率分别为 3 4 4%和 15 9% ;NAD组的血清CA1 2 5和PRL水平分别为 42 47± 6 97kU/L和 2 3 64± 6 98μg/L ,阳性率分别为 14 6%和 5 4%。AD组和NAD组的血清CA1 2 5和PRL水平以及阳性率之间的比较 ,均有显著性差异 (P <0 0 1)。AD组和NAD组的血清CA1 2 5和PRL水平与卵巢周期均无明显相关 (P >0 0 5 )。AD组的血清CA1 2 5和PRL水平的增高与合并症也均无显著相关 (P >0 0 5 )。结论 血清CA1 2 5和PRL测定可用来协助诊断AD。

Objective To investigate the diagnostic significance of serum CA 125 and Prolactin (PRL) detection in the patients with adnomyosis of uterus. Methods Serum CA 125 and PRL in the patients with or without adenomyosis of uterus were detected by the method of enzyme immunoassay and electochemiluminescence respectively. Results The levels of CA 125 and PRL of patients with adenomyosis were 58 91±5 42KU/L and 31 01±5 37KU/L respectively, and the positive rates were 14 6% and 5 4% respectively.There were significant differences of the levels and positive rates of CA 125 and PRL between the patients with or without adenomyosis (P<0 01). But there were no significant correlations between the levels of CA 125 and PRL and the follicular phase (P>0 05), and the levels of CA 125 and PRL were not related to the complications (P>0 05). Conclusion The detection of serum CA 125 and PRL could be used to help the diagnosis of adenomyosis of uterus.