摘要
为研究前列宁Ⅰ号 (主药 :牛膝、丹参、红花、黄柏 )的抗炎作用 ,观察高、低两个剂量组给实验动物灌胃 7天后 ,对二甲苯所致小鼠耳郭肿胀、角叉菜胶所致大鼠足肿胀、棉球所致大鼠肉芽增生的影响 ,并与强的松组对照。结果 :两个不同的剂量对上述三项炎症指标均有作用 ,且有一定的量效关系 ;在抗小鼠耳郭肿胀、大鼠足肿胀方面 ,高剂量前列宁Ⅰ号的作用与强的松相似。提示 。
In order to study the anti-inflammatory function of “Prostate-Calming Formula I' () and observe influence of its high and low dose by perfusion into the stomach on auricular tumefaction caused by dimethylbenzene in mice, foot tumefaction caused by carrageenin in rats and granulation proliferation caused by cotton ball in rats, in comparison with prednisone control group. The results showed that two different doses were all effective to the above-mentioned three indexes, with a certain dose-effect relationship. In resisting auricular tumefaction in mice and foot tumefaction in rats, the function of high dose of “Prostate-Calming Formula I' was similar to prednisone. The findings indicate that “Prostate-Calming Formula I' has a stronger anti-inflammatory function.
出处
《上海中医药大学学报》
CAS
2003年第2期45-46,共2页
Academic Journal of Shanghai University of Traditional Chinese Medicine
基金
河北省科技攻关项目 ( 992 61119D)
