芬太尼透皮贴剂不良反应观察

A Study of Adverse Drug Reactions of Durogesic

目的 :了解住院患者应用芬太尼透皮贴剂 (多瑞吉)的疗效及不良反应 ,促进临床合理用药。方法 :观察我院肿瘤科37例住院患者应用芬太尼透皮贴剂的情况 ,评价其止痛效果及不良反应发生率、程度和转归。结果 :芬太尼透皮贴剂止痛效果确切 ,癌痛缓解率达100% ;发生不良反应的有4例 ,发生率为10 8%。结论 :芬太尼透皮贴剂应用于癌痛治疗的效果确切 ,但要注意监测药物不良反应 。

OBJECTIVE:To study the incidence of adverse drug reactions(ADRs) and the rational use of Durogesic in in-patients METHODS:37 in-patients treated with Durogesic in Department of Oncology in our hospital were prospectively observed,and its analgesic efficacy and incidence,severity and the outcome of ADRs were evaluated RESULTS:The alleviating effect of Durogesic on carcinomatous pain was 100% Of 37 patients,ADRs were found in 4 cases with a ADR rate of 10 8% CONCLUSION:Durogesic is effective in clinical use,but attention should be paid to monitoring ADRs and avoiding irrational use of drug