硫酸镁微泵给药治疗儿童喘息性肺部疾病

Treatment of asthmatic lung diseases of children with magnesium sulfate delivered by microinfusion pump

目的 :观察硫酸镁微泵给药治疗儿童喘息性肺部疾病的疗效。方法 :按随机原则 ,观察组 5 8例硫酸镁每次 0 .0 5g/kg加入 10 %葡萄糖 30ml微泵维持静脉给药 3h ,喘憋严重者以 0 .0 5 g·kg-1·h-1微泵维持 3～ 5h。对照组 4 0例选用氨茶碱平喘。两组均给予积极抗感染、抗病毒等药物治疗。根据两组喘憋症状的缓解情况、肺部喘鸣音消失时间判断其疗效。结果 :观察组疗效高于对照组 (P <0 .0 0 5 ) ,肺部喘鸣音消失时间亦短于对照组 (P <0 .0 0 1)。结论 :硫酸镁微泵给药治疗儿童喘息性肺部疾病疗效肯定 ,安全性好 ,值得推广。

Objective:To observe the curative effect of magnesium sulfate(MgSO 4) delivered by microinfusion pump on asthmatic lung diseases of children.Methods:The patients with asthmatic lung diseases were randomly devided into two groups.The observation group was treated with a dose of 0.05 g/kg MgSO\-4 dissolved into 30 ml 10% glucose solution,which was maintained for three hours by microinfusion pump, to release the attack of gasp.In severe patients,MgSO 4 was delivered with a dose of 0.05 g/kg per hour,which was maintained for three to five hours by microinfusion pump.The control group was treated by aminophylline.The curative affect was evaluated by the alleviation of gasp and the time of rhonchi persisting in the lung.Results:The rate of effectiveness was higher in the observation group than in the control group( P <0.005).The time of rhonchi persisting in the lung was shorter in the observation group than in the control group( P <0.001).Conclusions:The results show that MgSO 4 delivered by microinfusion pump has definite effects on asthmatic lung diseases of children.This method is safe and worth to popularize.