2,2-二甲基-3-羟基丙酸甲酯的合成研究

Study on synthesis of methyl 2,2-dimethyl-3-hydroxypropionate

以工业甲醛和工业异丁醛为原料,通过羟醛缩合、氧化、酯化合成了2,2 二甲基 3 羟基丙酸甲酯,对其合成温度进行了探讨,反应总产率提高到21.9%,降低成本80%。

The methyl 2,2dimethyl3hydroxypropionate is synthesized from formaldehyde and isobutyraldehyde as starting substracts through aldol condensation, oxidation and esterification. The effect of temperature is discussed. The overall yield is increased to 21.9% and the cost is decreased 80%.