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急性心肌梗死静脉溶栓治疗后ST段再抬高临床意义探讨 被引量:6

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摘要 目的探讨急性心肌梗死 (AMI)静脉溶栓治疗中ST段再抬高产生的原因及临床意义。方法回顾性分析符合静脉溶栓标准的 10 7例AMI患者的临床资料 ,据溶栓后有无ST段再抬高而分为ST段抬高组 (A组 )和ST段未抬高组(B组 ) ,比较两组血管再通率、心律失常发生率、梗死后心绞痛发生率及心功能变化。结果两组溶栓后心律失常发生率无显著差异 (P >0 .0 5 ) ;A组血管再通率明显低于B组 (P <0 .0 5 ) ;梗死后心绞痛发生率、心功能不全发生率均高于B组 (P <0 .0 5 ) ;A组伴发糖尿病、高血压及高血脂明显多于B组 (P <0 .0 5 )。结论静脉溶栓治疗时ST段再抬高与患者合并糖尿病高血压、高血脂有密切关系。在溶栓后 1~ 4小时内出现ST段下降后再抬高或原有梗死相关部位ST段抬高再加重 ,其原因可能与溶栓后再灌注损伤及冠脉痉挛有关。而在 2 4小时后出现ST段再抬高可能与新的血栓形成引起再闭塞或梗死延展有关。
机构地区 解放军第
出处 《中国综合临床》 北大核心 2003年第7期658-659,共2页 Clinical Medicine of China
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