摘要
本文阐述小鼠鸦片受体基因敲除的技术,及其鸦片受体的3个亚型受体μ、δ、κ敲除的意义。
出处
《中国临床神经科学》
2003年第2期185-187,共3页
Chinese Journal of Clinical Neurosciences
参考文献13
-
1Mansour SL, Thomas KR, Capecchi MR. Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general stratgey for targeting mutations to non-selectable genes[J]. Nature. 1988,336(6197):348-352.
-
2Matthes HW, Maldonado R, Simonin F, et al. Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the muopioid-receptor gene[ J]. Nature, 1996, 383 : 819-823.
-
3Ghozland S, Matthes HW. Simonin F, et al. Motivational effects of cannabinoids are mediated by mu- and kappa-opioid receptors [ J ]. J Neurosci ,2002,22 : 1146-1154.
-
4Becker A, Grecksch G, Kraus J, et al. Rewarding effects of ethanol and cocaine in mu opioid receptor-deficient mice[ J ]. Naunyn Schmiedebergs Arch Pharmacol, 2002,365 : 296-302.
-
5LaBuda CA, Fuchs PN. The anxiolytic effect of acute ethanol or diazepam exposure is unaltered in μ-opioid receptor knockout mice [ J ]. Brain Res Bull ,2001,55:755-760.
-
6Sora I, Li XF, Funada M, et al. Visceral chemical nociception in mice lacking mu-opioid receptors: effects of morphine, SNC 80 and U-50,488 [J] .Eur J Pharmacol, 1999,366:3-5.
-
7LaBuda CJ, Sora I, Uhl GR, et al. Stress-induced analgesia in mu-opioid receptor knockout mice reveals normal function of the delta-opiod receptor systems[J]. Brain Res,2000,869:1-5.
-
8Nitsche JF, Schuller AG, King MA, et al. Genetic dissociation of opiate tolerance and physical dependence in delta-opioid receptor-1 and preproenkephalin knock-out mice[J] .J Neurosci,2002,22:10906-10913.
-
9Hutcheson DM. Matthes, H. W. D. Valjent, E., et al. Lack of dependence and rewarding effects of deltorphin Ⅱ in nu-opioid receptor-deficient mice[J]. Eur J Neurosci,2001,13:153-161.
-
10Filliol D, Ghozland S, Chluba J, et al. Mice deficient for delta- and muopioid receptors exhibit opposing alterations of emotional responses [ J ]. Nature Genet,2000,25 : 195-200.
同被引文献35
-
1Santosh Darisetty,Manu Tandan,Duvvuru Nageshwar Reddy,Rama Kotla,Rajesh Gupta,Mohan Ramchandani,Sandeep Lakhtakia,Guduru Venkat Rao,Rupa Banerjee.Epidural anesthesia is effective for extracorporeal shock wave lithotripsy of pancreatic and biliary calculi[J].World Journal of Gastrointestinal Surgery,2010,2(5):165-168. 被引量:13
-
2刘昊,石红艳,胡锦矗.四川梅花鹿春季昼夜活动节律与时间分配[J].兽类学报,2004,24(4):282-285. 被引量:33
-
3李剑虹,崔卫国,王宇,包军.猪Kappa阿片受体基因外显子部分序列单核苷酸多态性分析[J].Acta Genetica Sinica,2004,31(12):1369-1374. 被引量:2
-
4郭延蜀,郑慧珍.四川梅花鹿生命表和种群增长率的研究[J].兽类学报,2005,25(2):150-155. 被引量:10
-
5吕晓平,魏辅文,李明,杨光,刘海.中国梅花鹿(Cervus nippon)遗传多样性及与日本梅花鹿间的系统关系[J].科学通报,2006,51(3):292-298. 被引量:11
-
6Van putten G.Farming beyond the ability for pigs to adapt.Applied Animal Behaviour Science,1988,20(1/2): 63~71.
-
7Fraser A F,Broom D M.Farm Animal Behaviour and Welfare.London,Bailliere-Tindall,1990,327.
-
8Gonyou H W,Bergeron R.Is Abnormal Behaviour Really Abnormal? Proceedings of the 1995 Spring Conference Series,Prairie Swine Centre Inc,1995,7~10.
-
9Broom D M.Stereotypies as animal welfare indicators in Indicators relevant to farm animal welfare.In: Smidt D,eds.Indicators Relevant to Farm Animal Welfare.The Hague,Martinus Nijhoff,1983,81~87.
-
10Wiepkema P R.On the significance of ethological criteria for the assessment of animal welfare.In: Schmidt D,eds.Indicators Relevant to Farm Animal Welfare.The Hague,Martinus Nijhoff,1983,71~79.
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-
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-
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-
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-
2吕慎金,杨燕,魏万红.家畜行为及其遗传学研究进展[J].家畜生态学报,2008,29(1):6-9. 被引量:2
-
3吕慎金,杨燕,魏万红.OPRK1基因SNP与梅花鹿昼间行为性状的相关性[J].生态学报,2013,33(1):132-139.
-
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-
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-
6王鹏基,马继远.坦索罗辛联合呋塞米对输尿管结石体外冲击碎石术后患者的排石效果[J].临床合理用药杂志,2023,16(24):100-103. 被引量:5
-
7史劲飞,汤洁,戴筱筱,孙登群.不同剂量瑞马唑仑对肝内外胆管结石手术患者麻醉效果及血流动力学影响[J].川北医学院学报,2024,39(1):30-33. 被引量:1
-
8任常坦,苏双,刘敏.瑞芬太尼联合丙泊酚麻醉用于经尿道输尿管钬激光碎石术的效果分析[J].系统医学,2024,9(14):41-44.
-
1徐标.异丙肾上腺素产生的血管舒张作用是通过β_2亚型受体并依赖于内皮细胞和NO的产生[J].高血压杂志,1999,7(3):279-281. 被引量:1
-
2钟恒凡.长托宁临床研究进展[J].现代保健(医学创新研究),2008,5(3):36-36. 被引量:1
-
3秦索娜.坎地沙坦的药理特性及临床研究[J].中国新医药,2004,3(7):78-80. 被引量:4
-
4孙旗,吴俊芳,王津津,贺威琼,王彤.氯沙坦对血管紧张素Ⅱ诱导的心肌细胞核酸、蛋白质及c-fos基因表达抑制作用的研究[J].中国药理学通报,1999,15(6):540-542.
-
5林涛,何其通,刘环秋,麻海春,冯艳华.盐酸戊乙奎醚临床应用研究现状[J].吉林医学,2009,30(17):2047-2048. 被引量:3
-
6方彭华,郁梅,马银屏,李健,隋玉梅,史明仪.甘丙肽拮抗抑郁症的研究进展[J].神经疾病与精神卫生,2011,11(3):311-312.
-
7马兰花,李新旺,张静.5-羟色胺系统与药物成瘾的关系研究进展[J].中国药物滥用防治杂志,2008,14(4):223-226. 被引量:4
-
8聂惠贞,李薇,聂瑞丽,殷明.神经元烟碱α4β2亚型受体与神经系统疾病的关系[J].上海交通大学学报(医学版),2009,29(6):744-746. 被引量:1
-
9王耀霞,杨志宏,岳旺,刘占涛,韩庆方.姜辣素在2种呕吐动物模型中止呕作用机制的探讨[J].沈阳药科大学学报,2009,26(2):134-137. 被引量:22
-
10郑继旺.美国成瘾性研究中心简介[J].中国药物依赖性杂志,1991,6(4):8-10.