术中探测^(99)Tc^m-MIBI分布判断肺部肿瘤及淋巴结良恶性的临床价值

The Clinical Value of Intraoperative Detecting the Distribution of ^(99)Tc^m-MIBI to Differentiate the Benign or Malignant Foci and Lymph Node of Lung

用手持式γ探测仪(GDP)探测术前注射^(99)Tc^m-MIBI的30例肺部病变患者原发病灶及淋巴结中的分布以判定其良恶性。结果显示肺癌患者的原发灶GDP检测结果均为阳性,而良性病变患者的检测结果均为阴性。在本工作条件下,GDP探测淋巴结转移的阳性检出率为100％,特异性93.6％,准确率94.4％。此研究证明^(99)Tc^m-MIBI术中γ探测判断肺部肿瘤及淋巴结良恶性可较好克服常规临床显像的不足,具有阳性检出率高、准确性好、特异性强的优点。

The distribution of foci and lymph nodes of thirty patients injected with 99Tcm-MIBI are detected to differentiate which is benign or malignant by γ-detecting Probe (GDP) intraoperatively. The results of GDP detecting the malignant foci are all positive, and the benign foci are all negative. The positive rate of GDP detecting the metastatic lymph node is 100%, the specificity is 93. 6%, and the accuracy is 94. 4% under the study condition. The results of the study indicates that the method of intraoperative detecting the focus and lymph node by GDP and judging which is benign or malignant with 'Tcm-MIBI injection is of high sensitivity,good accuracy and specificity.