雾化吸入治疗耐多药肺结核

Inhalation in Treating Multi-drug Resistant Pulmonary Tuberculosis

目的 探讨用雾化吸入治疗耐多药肺结核的治疗价值。方法 将 72例耐多药肺结核患者随机分为治疗组和对照组。治疗组强化期采用雾化吸入加化疗 ,对照组只加化疗。结果 强化期结束时 ,经雾化吸入治疗组症状明显改善者 90 .6% ,痰菌阴转率 87.5 % ,病灶显著吸收率 87.5 % ;明显高于单纯化疗组的 5 6.3 % ,5 0 .0 % ,3 7.5 % (P <0 .0 5 )。结论 用雾化吸入治疗耐多药肺结核疗效显著 。

Objective To evaluate the clinical value of inhalation in treating multi-drug resistant pulmonary tuberculosis. Methods Patients with multi-drug resistant pulmonary tuberculosis were randomly divided into two groups, the experiment group and the control group.The experiment group was treated by inhalation and general antituberculotic,and the control group only by general antituberculotic. Results After the therapy of initial phase,90.6% of patient in the experiment group had their symptoms greatly improved, the sputum conversion rates in the experiment group were 87.5%, the patients with foci markedly absorbed were 78.1%,all of which were higher than the control group (56.3%,50.0%and 37.5%resoectively)(P<0.05).Conclusions The efficacy of inhalation is better than the chemotherapy in treating multi-drug resistant pulmonary tuberculosis. No complication and obvious adverse reaction are observed.