1Cao G, Kuriyama S, Gao J, et al. Gene therapy for hepatocellular carcinoma based on tumour-selective suicide gene expression using the alpha-fetoprotein (AFP) enhancer and a housekeeping gene promoter[J]. Eur J Cancer, 2001,37: 140-147.
2Majumdar AS, Hughes DE, Lichtsteiner SP, et al. The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters[J]. Gene Ther, 2001. 8: 568-578.
3Krohne TU, Shankara S, Gelssler M, et al. Mechanisms of cell death induced by suicide encoding purine nucleoside phosphorylase and thymidine kinase in human hepatocllular carcinoma cell in vitro[J]. Hepatology, 2001, 34: 511-518.
4Cortes ML, Garcia-Escudero V, Hughes M, et al. Cyanide bystander effect of the linamarase/linamarin killer-suicide gene therapy system[J]. J Gene Med, 2002, 4: 407-414.
5Gnant MF, Puhlmann M, Alexander HR, et al. Systemic administration of a recombinant vaccinia virus expressing the cytosine deaminase gene and subsequent treatment with 5-fluorocytosine leads to tumor-specific gene expression and prolongation of survival in mice[J]. Cancer Res, 1999, 59: 3396-403.
6Drozdzik M, Qian C, Xie X, et al. Combined gene therapy with suicide gene and interleukin-12 is more efficient than therapy with one gene alone in a murine model of hepatocellular carcinoma[ J ].J Hepatol, 2000, 32: 279-286.
7Kawashita Y, Ohtsuru A, Kaneda Y, et al. Regression of hepato-cellular carcinoma in vitro and in vivo by radiosensitizing suicide gene therapy under the inducible and spatial control of radiation[J]. Hum Gene Ther, 1999, 10: 1509-1519.
8Kanazawa T, Urabe M, Mizukami H, et al. Gamma-rays enhance rAAV-mediated transgene expression and cytocidal effect of AAV-HSVtk/ganciclovir on cancer cells[ J]. Cancer Gene Ther, 2001,8 : 99-106.
9Nakamura H, Mullen JT, Chandrasekhar S, et al. Multimodality therapy with a replication-conditional herpes simplex virus 1 mutant that expresses yeast cytosine deaminase for intratumoral conversion of 5-fluorocytosine to 5-fluorouracil[ J]. Cancer Res, 2001, 61 :5447-5452.
10Kenneth R, Mark W, Dell P, et al. Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization [ J ].Hum Gene Ther, 2000, 11 : 67-76.