摘要
为了提高头孢菌素 C 的产量,通过对头孢菌素 C 产生菌顶头孢霉菌 B42—V2进行紫外线和亚硝酸的复合诱变处理,得到变株 B42—V2N,单位提高10.04%,且遗传性状非常稳定。实验表明:紫外线和亚硝酸复合诱变,操作简便、安全高效,所选育菌种遗传性状稳定。
In order to improve the prodution of Cephalosporin Mutant B42—V2N with better genetic stability was obtained and 10.04 percent of yields was increased by inducing Cephalospori- um acremonium B42—V2 with UV and HNO_2 in this experiment.Experiment shows that the com- pound mutagens of UV and HNO_2 has features of easy operation,safety,good result and stability for mutant selected.
出处
《黑龙江医药》
CAS
2003年第4期283-284,共2页
Heilongjiang Medicine journal
关键词
紫外线
亚硝酸
复合诱变
顶头孢霉菌
选育
应用
Cephalosporin C
Cephalosporium acremonium
UV
HNO_2
Mutation breading
