1Giannini E,Risso D,Botta F,et al.Validity and clinical utility of the aspartate aminotransferase.alanine aminotransferase ratio in assessing disease severity and prognosis in patients with hepatitis C virus—related chronic liver disease.Arch Intern Med,2003,163:218—224.
3Shi Y.Mammalian RNAi for the masses Trends Genet,2003,19:9-12.
4Kawasaki H,Taira K.Short hairpin type of dsRNAs that are controlled by tRNA(Val)promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells.Nucleic Acids Res,2003,31:700-707.
5Bosher J M,Labouesse M RNA interference:genetic wand and genetic watchdog.Nature Cell Biol,2000,2:E31-E36.
6Park WS,Miyano-Kurosaki N,Hayafune M,et al. Prevention of HIV-1 infection in human peripheral blood mononuclear cells by specific RNA interference.Nucleic Acids Res,2002,30:4830-4835.
7Surabhi RM,Gaynor RB RNA interference directed against viral and cellular targets inhibits human immunodeficiency virus type 1 replication.J Virol,2002,76:12963-12973.
8Seo MY,Abrignani S,Houghton M,et a1.Small interfering RNA-mediated inhibition of hepatitis C virus replication in the human hepatoma cell line Huh-7.J Virol,2003,77:810-812.
9Randall G,Grakoui,Rice CM.Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs.PNAS USA,2003,100:235-240.
10Wilson JA,Jayasena S,Khvorova A,et al. RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells.PNAS USA,2003,100:2783-2788.
7AKHTAR S, BENTER I. Toxieogenomics of non-viral drug delivery systems for RNAi: Potential impact on siRNA-mediated gene silencing activity and specificity [J]. Adv Drug Deliv Rev,2007,59(2-3):164-182.
