用PCR技术研究HBsAg阳性者血清HBV-DNA与e系统的关系

Using PCR to Research the Relation between Serum HBV-DNA and e System in Asymptomatic HBsAg Positive Patients

作者应用聚合酶链反应(PCR)对经酶联免疫法检出的211份HBsAg阳性者进行HBV-DNA检测。同时与e系统检测结果比较,发现HBeAg阳性组HBV-DNA阳性率为97.8％,而抗-HBe阳性组HBV-DNA阳性率为39.7％(P<0.01);应用聚合酶链反应检测HBV-DNA对于确切了解HBsAg阳性者HBV感染状况和传染性有一定意义。

The authers have used PCR to research the relation between serum HBV-DNA and e system in 211 asyptomatic HBsAg positive patients detected with ELISA. In HBeAg positive group 97. 8%(89/91) was HBV-DNA positive and in anti-HBe poitive group only 39. 7% (31/78) was HBV-DNA positive (P<0. 01). It was suggested that Using PCR to detect HBV-DNA has fairly clinical and surveillant significant for HBsAg positive patients.