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多巴胺受体与精神分裂症关系的研究现状 被引量：10

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摘要 DAR是能与DA特异性结合的蛋白质类物质。目前分为D_1、D_2、D_3、D_4和D_5五种类型。因D_1、D_3、D_5能激活腺甘酸环化酶(AC),使cAMP的含量增加,故将它们合称之为D_1受体(简称D_1);反之,D_2和D_4能抑制AC酶活力,使cAMP的含量减少,故称为D_2受体(简称D_2)。DAR能通过异源二聚化而将信号传递下去。DAR与精神分裂症的发病关系密切。
作者 刘建新 李栓德
机构地区 解放军第三医院神经外科研究所暨全军精神病外科中心
出处 《国外医学（临床生物化学与检验学分册）》 2003年第4期201-203,共3页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
关键词 多巴胺受体 配体 精神分裂症 DAR
分类号 R749.3 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献17

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二级参考文献4

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共引文献8

同被引文献52

  • 1李拴德,马文涛,杨来启,王晓峰,刘建新,刘光雄.立体定向毁损杏仁核对大鼠脑内单胺递质影响的实验研究[J].西北国防医学杂志,2004,25(4):257-259. 被引量：3
  • 2陈亮,石年,董杰,李涛,陈丹.雌二醇对溴氰菊酯染毒大鼠皮层突触体神经毒性的影响[J].中华劳动卫生职业病杂志,2004,22(1):22-25. 被引量：2
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引证文献10

二级引证文献13

国外医学（临床生物化学与检验学分册）
2003年 第4期

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