肝炎后肝硬化时肝脏体积变化的临床研究

A Clinical Study of the Variety in Liver Volume Posthepatitic Cirrhosis

利用数字图像处理系统和“三维信息提取与三维图像重建”的方法,通过肝脏 CT 断层影像,成功地重建了活体肝脏三维图像,并测出活体肝脏体积。为排除体格差异,再根据体表面积,求出每单位体表面积的肝脏体积。临床应用42例,其中非肝硬化组8例,均值为773.88±69.17cm^3/m^2;肝炎后肝硬化组34例,均值为493.72±102.50cm^3/m^2。两组均值的差异显著(P<0.001)。肝炎后肝硬化组中,各级肝功能的肝体积无统计学差异(P>0.05)。肝体积大于400cm^3/m^2者与小于400cm^3/m^2者的术后顺利康复率差异显著(P<0.01)。

By means of the digital image-processing system and the moder apparatus technique,the authors attempted successfully for the first time in building three dime- nsional image of the liver in vivo,and then measured the liver volume accurately.To eliminate physical differences of the patients,the liver volume in unit per body surface area was counted.Clinical application in 8 noncirrhotic patients as the control group with a mean value of 773.88±69.17cm^3/m^2,and 34 posthepatitic cirrhosis group with a mean value of 493.72±102.50cm^3/m^2 was achieved.The difference of the two groups is significant(p<0.001).The liver volume had no significant statistic difference among various laboratory tests of liver function in the posthepatitic cirrhosis group(p>0.05). However the post-operative recovery rate of patients depended upon the factor of liver volume a lot that larger than 400 cm^3/m^2 was much better than small ones(p<0.01). Altogether 42 cases had been prelimarily measured in the study.