三角形子宫切除对绝经前女性骨代谢及精神心理的影响

Effect of triangle hysterectomy on bone metabolism and mental state of pre menopausal women

目的观察三角形子宫切除术对患者骨代谢及精神心理影响。方法选取因子宫良性病变行三角形子宫切除术患者50例为研究组,子宫附件正常的妇女50例为对照组。采用化学发光法及酶联免疫吸附法(ELISA法)检测术前、术后1年患者及对照组妇女血碱性磷酸酶(ALP)、骨钙素(BGP)、尿脱氧吡啶(DPD)水平。采用中国健康问卷(CHQ-12)测评术前及术后1年精神心理状况。结果三角形子宫切除组术后1年ALP、BGP、DPD水平与术前及对照组相比差异均无统计学意义(P>0.05),在精神心理方面术前、术后CHQ-12评分差异无统计学意义(P>0.05)。结论绝经前三角形子宫切除对患者骨代谢及精神心理无明显影响。

Objective To compare the effects on triangle hysterectomy on bone metabolism and mental state of pre menopausal women. Methods 50 patients with triangle hysterectomy for uterine benign lesion were selected as study group. 50 fertile women were enrolled as the control group. Serum alkaline phosphatase( ALP),bone gla protein( BGP) and deoxypyridinoline( DPD) of study group preoperative and postoperative 1 year patients and control groupwere detected by chemiluminescence method and enzyme linked immunosorbent assay( ELISA) method. The results of the questionnaire on psychological health were colected and compared. Results There were no significant differences in the level of serum ALP,BGP and DPD in study group women with triangle hysterectomy compared with those in fertile women( P > 0. 05). Triangle hysterectomy had no obvious effect on psychological health( P > 0. 05). Conclusion There is no obvious effect on bone metabolism and psychological health after triangle hysterectomy for the pre-menopausal patients.