卡前列素氨丁三醇预防高危妊娠产妇产后出血的临床疗效

Clinical efficacy of carboprost tromethamine in preventing postpartum hemorrhage of high- risk pregnancy lying- in woman

目的探讨卡前列素氨丁三醇预防高危妊娠产妇产后出血的临床疗效。方法选取2013年3月—2015年5月台安县妇幼保健院收治的73例高危妊娠产妇,随机分为研究组37例和对照组36例。两组产妇均行剖宫产,对照组给予米索前列醇和缩宫素预防产后出血,研究组给予卡前列素氨丁三醇和缩宫素预防产后出血,比较两组产妇产后2、24h出血量及输血、产后出血、子宫切除发生率。结果研究组产妇产后2、24h出血量少于对照组,产妇输血、产后出血发生率均低于对照组,差异有统计学意义(P<0.05)。结论卡前列素氨丁三醇预防高危妊娠产妇产后出血的疗效显著,可有效减少产后出血量,降低产后出血发生率,保障母婴生命安全。

Objective To study the clinical efficacy of carboprost tromethamine in preventing postpartum hemorrhage of high- risk pregnancy lying- in woman. Methods A total of 73 high- risk pregnancy lying- in woman in Maternal and Child Health Hospital of Taian County from March 2013 to May 2015 were selected,they were randomly divided into research group( n = 37) and control group( n = 36). The two groups were all given cesarean delivery,contrlo group were given misoprostol and oxytocin to prevent postpartum hemorrhage,research group were given carboprost tromethamine and oxytocin to prevent postpartum hemorrhage,the bleeding volume after cesarean delivery 2,24 h and incidence rate of transfusion,postpartum hemorrhage,hysterectomy between the two groups were compared. Results The bleeding volume after cesarean delivery 2,24 h of research group were less than control group, incidence rate of transfusion, postpartum hemorrhage were lower than control group,the differences were statistically significant( P < 0. 05). Conclusion The clinical efficacy of carboprost tromethamine prevent postpartum hemorrhage of high- risk pregnancy lying- in woman is remarkable,it can effectively derease bleeding volume after cesarean delivery,reduse incidence rate of postpartum hemorrhage,ensure maternal and child safety.