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甲氨蝶呤对类风湿关节炎患者动脉粥样硬化的保护作用 被引量：2

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摘要 大量临床证据表明,类风湿关节炎(rheumatoid arthritis,RA)患者冠心病(coronary heart disease,CAD)发病率较一般人群高且早,RA可能是CAD的独立危险因素[1],心血管疾病成为RA主要的死亡原因。随着RA患者病情发生、发展,动脉粥样硬化(Atherosclerosis,AS)发生率较正常人明显增高,在RA患者中,发生AS主要与炎性因子、脂质谱异常、氧化应激、
作者 王茂竹 李法琦
机构地区 重庆医科大学附属第一医院老年病科
出处 《临床合理用药杂志》 2016年第10期166-168,共3页 Chinese Journal of Clinical Rational Drug Use
关键词 类风湿关节炎 动脉粥样硬化 甲氨蝶呤 保护作用
分类号 R593.22 [医药卫生—内科学] R543.5 [医药卫生—心血管疾病]
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参考文献27

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二级参考文献67

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共引文献32

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临床合理用药杂志
2016年 第10期

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