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化疗致恶心、呕吐的机制及治疗研究进展 被引量：16

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摘要 在化疗所有副反应中,最常见的是消化道反应,而其中最常见的是恶心、呕吐。这些反应使患者感到痛苦,严重者可引起自身代谢失调、电解质紊乱等。患者常常因严重的恶心呕吐反应推迟化疗,甚至拒绝下一步化疗,从而影响治疗的疗效。在过去几十年中,恶心、呕吐反应的处理有较大提高,使患者痛苦得到极大减轻,进而使化疗达到一定的目的,但目前对于化疗引起恶心、呕吐反应的机制尚未明确。1定义与分类1.1恶心及呕吐定义恶心是指上腹部的不适感,
作者 徐红丽 赵建武
机构地区 遵义医学院 贵州省人民医院
出处 《临床合理用药杂志》 2016年第10期174-175,共2页 Chinese Journal of Clinical Rational Drug Use
关键词 化疗 恶心呕吐 治疗 机制
分类号 R730.53 [医药卫生—肿瘤]
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参考文献9

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  • 2Charles C. Horn,Marc Ciucci,Arun Chaudhury.??Brain Fos expression during 48 h after cisplatin treatment: Neural pathways for acute and delayed visceral sickness(J)Autonomic Neuroscience: Basic and Clinical . 2006 (1)
  • 3Hiroki Ueda,Chigusa Shimono,Tomoyasu Nishimura,Megumi Shimamoto,Hiroki Yamaue.??Palonosetron exhibits higher total control rate compared to first?generationserotonin antagonists and improves appetite in delayed?phase chemotherapy?inducednausea and vomiting(J)Molecular and Clinical Oncology . 2014 (3)
  • 4Naomi Mizukami,Masanori Yamauchi,Kazuhiko Koike,Akihiko Watanabe,Koji Ichihara,Naoya Masumori,Michiaki Yamakage.??Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Patients Receiving Highly or Moderately Emetogenic Chemotherapy: A Randomized, Double-Blind, Placebo-Controlled Study(J)Journal of Pain and Symptom Management . 2014 (3)
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共引文献1

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引证文献16

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临床合理用药杂志
2016年 第10期

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