泮托拉唑联合注射用白眉蛇毒血凝酶治疗上消化道出血的临床疗效

Clinical efficacy of pantoprazole combined with hemocoagulase for injection in the treatment of upper gastrointestinal bleeding

目的探讨泮托拉唑联合注射用白眉蛇毒血凝酶治疗上消化道出血的临床疗效。方法选取2012年1月—2014年1月在江铜集团(德兴)医院诊治的80例上消化道出血患者,随机分为对照组和试验组,各40例。对照组采用常规方法治疗,试验组采用泮托拉唑联合注射用白眉蛇毒血凝酶治疗,比较两组患者临床疗效及不良反应发生情况。结果试验组总有效率高于对照组,差异有统计学意义(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论泮托拉唑联合凝血酶治疗上消化道出血的临床疗效显著,且药物不良反应少。

Objective To investigate the clinical effects of pantoprazole combined hemocoagulase for injection in the treatment of upper gastrointestinal bleeding. Methods A total of 80 case of patients with upper gastrointestinal bleeding were selected from January 2012 to January 2014 in the Jiangtong Group( Dexing) Hospital,which were divided into the control group and the experimental group,40 cases in each group. The control group was treated with conventional methods,the experimental group was treated with pantoprazole combined hemocoagulase for injection,the two groups of clinical effect and adverse reactions were compared. Results The total effective rate of the experimental group was higher than control group( P < 0. 05).There was no significantly difference of the two groups of the adverse reaction rate( P > 0. 05). Conclusion Pantoprazole combined with hemocoagulase for injection have a significant clinical efficacy in the treatment of upper gastrointestinal bleeding,and has less adverse reactions.