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氯沙坦治疗社区原发性高血压病对血压控制及蛋白尿改善的效果 被引量:3

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摘要 目的探讨氯沙坦治疗社区原发性高血压病对血压控制及蛋白尿改善的效果。方法选择2014年9月—2015年9月宁波市鄞州区古林镇卫生院收治的80例原发性高血压病患者,按照随机数表法分为对照组(40例)和观察组(40例),对照组给予氢氯噻嗪治疗,观察组给予氯沙坦治疗,比较两组患者治疗前后血压〔收缩压(SBP)、舒张压(DBP)〕及蛋白尿〔尿微量清蛋白(m AIb)、尿β2微球蛋白(β2-MG)〕及不良反应情况。结果治疗前两组患者SBP、DBP比较,差异无统计学意义(P>0.05),治疗后观察组SBP、DBP低于对照组,差异有统计学意义(P<0.05)。治疗前两组患者m AIb、β2-MG水平比较,差异无统计学意义(P>0.05),治疗后观察组m AIb、β2-MG水平低于对照组,差异有统计学意义(P<0.05)。两组患者均未发生不良反应。结论氯沙坦治疗社区原发性高血压病可对患者血压进行有效控制并改善蛋白尿水平。
作者 王静
出处 《临床合理用药杂志》 2016年第12期79-80,共2页 Chinese Journal of Clinical Rational Drug Use
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