抗菌药物专项整治活动对我院妇产科剖宫产围术期预防性应用抗菌药物的影响

Influences on perioperative prophylactic use of antimicrobial drugs of the antibiotics rectification activities during cesarean section in our hospital

目的考察抗菌药物专项整治活动对我院妇产科剖宫产围术期预防性应用抗菌药物的影响。方法采用回顾性调查的方法调取2011年、2013年、2015年第一季度所有的妇产科剖宫产手术病例,对其抗菌药物的使用情况进行汇总分析。结果抗菌药物选择的合理率由2011年的33.3%,明显提升到2013年的90.0%(P<0.05),并在2015年进一步提升到96.1%(P>0.05);预防用药时机的合理率由2011年的7.7%明显提升到2013年的52.5%(P<0.05),到2015年进一步提升到93.5%(P<0.05);用药疗程在术后24h内停药率由2011年的6.4%明显提升到2013年的68.8%(P<0.05),到2015年进一步提升到97.4%(P<0.05)。结论抗菌药物专项整治活动明显提升了我院妇产科剖宫产围术期的抗菌药物应用合理性,且能持续改进,并没有出现反弹现象。

Objective To investigate the influences on perioperative prophylactic use of antimicrobial drugs of the an-tibiotics rectification activities during cesarean section in our hospital obstetrics and gynecology. Methods All cases of cesare-an section in 2011,in 2013 and in 2015 in the first quarter were obtained by using retrospective method,and then summarized and analyzed on the use of antibiotics. Results The reasonable rate of antimicrobial drug selection form 33. 3% in 2011 to raised significantly to 90. 0% in 2013(P ﹤ 0. 05),to further raise to 96. 1% in 2015(P ﹥ 0. 05);the reasonable rate of proph-ylaxis timing from 7. 7% in 2011 to improved significantly to 52. 5%(P ﹤ 0. 05)in 2013,to further improve to 93. 5% in 2015 (P ﹤ 0. 05);the rate of medication duration within 24h from 6. 4% in 2011 to improved significantly to 68. 8% in 2013(P ﹤0. 05),to further increase to 97. 4% in 2015(P ﹤ 0. 05). Conclusion The rectification activities of antimicrobial agents sig-nificantly improve the reasonable antimicrobial use,and can continue to improve,and no rebound phenomenon.