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短疗程抗菌药物治疗肝硬化合并原发性腹膜炎的临床疗效及合理性分析 被引量:1

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摘要 目的探讨短疗程抗菌药物治疗肝硬化合并原发性腹膜炎的临床疗效及合理性。方法选取2006年1月—2014年6月天津市第二人民医院收治的肝硬化合并原发性腹膜炎患者256例。根据用药疗程不同分为短期组94例与长期组162例。观察两组患者治疗48h或72h的应答率、治愈率以及30d存活率。结果两组患者应用喹诺酮类(左氧氟沙星)、三代头孢、酶抑制剂类抗菌药物的48h或72h应答率、治愈率比较,差异无统计学意义(P>0.05)。两组患者30d存活率比较,差异无统计学意义(P>0.05)。两组肝肾综合征治愈率、30d存活率比较,差异无统计学意义(P>0.05)。结论短疗程与长疗程抗菌药物治疗肝硬化合并原发性腹膜炎的临床疗效相当,但短疗程抗菌药物治疗肝硬化合并原发性腹膜炎更合理。
出处 《临床合理用药杂志》 2016年第15期47-48,共2页 Chinese Journal of Clinical Rational Drug Use
基金 天津市卫生局科技基金项目(06KZ36)
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参考文献12

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