大剂量肾上腺素对心脏骤停患者的抢救效果观察

Rescue effect of high-dose epinephrine in cardiac arrest

目的观察心脏骤停患者采用大剂量肾上腺素进行抢救的效果。方法将92例心脏骤停患者随机分为观察组和对照组各46例。在常规抢救的基础上,对照组采用常规剂量的肾上腺素治疗,观察组则采用大剂量肾上腺素治疗,对比2组患者的复苏成功率和自主循环、呼吸恢复情况。结果观察组复苏成功率为47.83%高于对照组的26.09%,差异有统计学意义(P<0.05)。观察组自主循环恢复率和自主呼吸恢复率均高于对照组,差异有统计学意义(P<0.05)。2组存活>1d率比较差异无统计学意义(P>0.05)。结论和常规剂量肾上腺素治疗比较,大剂量对于心脏骤停患者具有更显著的抢救效果,有助于促进患者自主循环和呼吸的迅速恢复,提高心肺复苏的成功率,挽救患者的生命,临床应用价值更显著。

Objective To observe the rescue effect of high dose adrenaline in cardiac arrest.Methods 92 cases patients with cardiac arrest were randomly divided into observation group and control group,each of 46 cases.On the basis of conventional rescue,The control group received conventional doses of epinephrine,Observation group is using high-dose epinephrine.After treatmtent,compared the success rate of recovery of spontaneous circulation,breathing recovery.Results The recovery success rate of observation group( 47.83%) was higher than that of control group( 26.09%),the difference was statistically significant( P < 0.05).The ROSC rate and the rate of recovery of spontaneous breathing of observation group were higher than that of control group,the difference was statistically significant( P < 0.05).The survival > 1d rate of 2 groups were no statistically significant( P > 0.05).Conclusion Comparison of conventional-dose epinephrine therapy,large doses for cardiac arrest patients have a more significant effect rescue.Contribute to the promotion of spontaneous circulation and breathing,rapid recovery.Improve the success rate of cardiopulmonary resuscitation to save the lives of patients,the clinical value of more pronounced.