我院2015年药品不良反应109例报告分析

Analysis on 109 cases of adverse drug reaction report in our hospital during 2015

目的了解我院药品不良反应(ADR)的发生特点,促进临床合理用药。方法对我院2015年收集的ADR报告109例的给药途径、来源及科室分布、药品种类及损害系统等进行统计分析。结果静脉滴注方式给药引发的ADR最多,占66.06%,口服给药占33.94%;ADR主要来源于内科51例(46.79%),皮肤科11例(10.09%);由抗菌药物导致的ADR所占比例为48.60%;皮肤损害的ADR约为总报告例数的49.5%。结论临床应重视药品不良反应的报告和监测工作,减少或避免ADR的发生。

Objective To study the characteristies of adverse drug reaction( ADR) in our hospital and to promate ration clinical drug use. Methods 109 ADR cases collected during 2015 in our hospital were analyzed statistically,such as route of administration,distribution of source and distribution,types of drugs and damage system. Results Intravenous infusion of ADR caused the most which counted for 66. 06%,oral administration counted for 33. 94%; ADR mainly derived from Department of internal medicine that 51 cases counted for 46. 79%,11 cases( 10. 09%) in the department of dermatology; the occurrence of ADR induced by antibacterials counted for 48. 60%; ADR affecting skin counted for 49. 5%. Conclusion Clinical attention should be paid to the report and monitoring of adverse drug reaction,to reduce or avoid the occurrence of ADR.