地佐辛防治妇科腹腔镜手术患者苏醒期躁动的效果观察

The effect of dezocine controlling emergence agitation of patients undergoing laparoscopic gynecological surgery treatment

目的探讨地佐辛防治妇科腹腔镜手术患者苏醒期躁动的效果,为临床防治苏醒期躁动提供依据。方法选取长治市妇幼保健院2014—2015年行妇科腹腔镜手术的患者90例,按照随机数字表法将其分为地佐辛组和芬太尼组,各45例。手术结束前10min,地佐辛组给予静脉滴注地佐辛10mg,芬太尼组静脉滴注芬太尼0.1mg。手术过程中常规监测患者心率(HR)、平均动脉压(MAP)、血氧饱和度(SpO_2)并进行比较。记录两组患者拔管即时(T1)、拔管30min(T2)、拔管1h(T3)的Riker镇静和躁动评分(SAS)、视觉模拟评分(VAS)并进行比较。结果HR、MAP的时间和方法间有交互作用(P<0.05);组间比较,差异有统计学意义(P<0.05);时间间比较,差异有统计学意义(P<0.05)。SpO_2时间和方法间无交互作用(P>0.05);组间比较,差异无统计学意义(P>0.05);时间间比较,差异无统计学意义(P>0.05)。地佐辛组患者不同时点的HR、MAP低于芬太尼组,差异有统计学意义(P<0.05);地佐辛组与芬太尼组患者的SpO_2水平比较,差异无统计学意义(P>0.05)。SAS、VAS评分的时间和方法间有交互作用(P<0.05);组间比较,差异有统计学意义(P<0.05);时间间比较,差异有统计学意义(P<0.05)。地佐辛组患者不同时点的SAS、VAS评分低于芬太尼组,差异有统计学意义(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论地佐辛防治妇科腹腔镜手术患者苏醒期躁动的效果较好。

Objective To investigate the effect of dezocine controlling emergence agitation of patients undergoing laparoscopic gynecological surgery treatment,in order to provide basis for clinical prevention and treatment of emergence agitation.Methods In Maternal and Child Health Hospital of Changzhi from 2014 to 2015 90 gynecological laparoscopic surgery patients were selected,which were randomly divided into dezocine group and fentanyl group,45 cases in each. 10 min before the end of surgery,dezocine group received intravenous injection of dezocine 10 mg,fentanyl group received intravenous injection of fentanyl 0. 1mg. During the operation with routine monitoring of heart rate( HR),mean arterial pressure( MAP),oxygen saturation( SpO_2) and compared. Extubation immediately( T1),extubation 30min( T2),extubation 1H( T3) R Iker sedation and agi-tation score( SAS),visual analogue scale( VAS) between the two groups were recorded and compared. Results There were significant interaction time in HR,MAP between treatment method and time( P < 0. 05); there were statistically significant differences in HR,MAP among different time points( P < 0. 05); there were statistically significant differences in HR,MAP among groups( P < 0. 05). There were not significant interaction time in SpO_2between treatment method and time( P > 0. 05);there were not statistically significant differences in SpO_2among different time points( P > 0. 05); there were not statistically significant differences in SpO_2among groups( P > 0. 05). Dezocine group at different time points in patients with HR were lower than fentanyl group; dezocine group at different time points in patients with MAP were lower than fentanyl group( P < 0. 05);SpO_2level between the two groups showed no significant differences( P > 0. 05). There were significant interaction time in SAS,VAS scores between treatment method and time( P < 0. 05); there were statistically significant differences in SAS,VAS scores among different time points( P < 0. 05); there were statistically significant differences in SAS,VAS scores among groups( P <0. 05). Dezocine group at different time points in patients with the SAS,VAS score were lower than fentanyl group( P <0. 05). Adverse reaction rate between the two groups showed no significant differences( P > 0 05). Conclusion The effect of dezocine controlling emergence agitation is better in patients undergoing laparoscopic gynecological surgery treatment.