中西医结合治疗缺血性中风病(气虚血瘀型)的临床疗效

Clinical efficacy of traditional Chinese and Western medicine in the treatment of ischemic stroke(Qi deficiency and blood stasis)

目的探讨中西医结合治疗缺血性中风病(气虚血瘀型)的临床疗效。方法选取2011年9月—2015年9月山东体育学院附属医院收治的急性期缺血性中风患者60例,随机分为治疗组与对照组,各30例。治疗组给予自拟益气活血汤联合奥扎格雷钠注射液治疗,对照组给予奥扎格雷钠注射液治疗。比较两组患者中医证候积分、神经功能缺损程度、临床综合疗效及不良反应发生情况。结果两组患者第1、7天中医证候积分比较,差异无统计学意义(P>0.05);治疗组第15天后中医证候积分低于对照组,临床神经功能缺损程度总有效率及临床综合疗效总有效率高于对照组,差异有统计学意义(P<0.05)。两组患者治疗期间均未发现任何不良反应。结论自拟益气活血汤联合奥扎格雷钠注射液治疗缺血性中风疗效确切,能有效改善脑神经功能缺损,提高患者的生存质量,且用药安全,疗效可靠。

Objective To investigate the clinical effect of traditional Chinese and Western medicine in treating ischemic stroke( Qi deficiency and blood stasis). Methods A total of 60 acute ischemic stroke patients were selected from September 2011 to September 2015 in the Affiliated Hospital of Shandong Sports Institute,which were randomly divided into treatment group and control group,30 cases in each. The treatment group received Yiqi Huoxue decoction combined with ozagrel sodium injection treatment,the control group was given ozagrel sodium injection treatment. The TCM syndromes,degree of neurologic impairment,comprehensive clinical efficacy and occurrence of adverse reactions between the two groups were compared. Results After 1,7 days TCM syndrome score between the two groups showed no significant differences( P > 0. 05); 15 days after treatment TCM syndrome score of the treatment group was lower than the control group,the degree of neurological impairment and the total effevtive rate of clinical comprehensive therapeutic effect were higher than the control group,the differences were statistically significant( P < 0. 05). No adverse happened in the two groups during treatment. Conclusion Yiqi Huoxue decoction combined with ozagrel sodium injection have exact effect in treating ischemic stroke,can effectively improve the neurologic impairment,improve the life quality of patients,and the drug safety,the curative effect is reliable.