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重组人脑利钠肽治疗难治性心力衰竭的临床观察 被引量:1

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摘要 目的观察重组人脑利钠肽(rh-BNP)治疗难治性心力衰竭的疗效。方法将难治性心力衰竭患者100例随机分为观察组和对照组各50例,对照组予常规治疗,观察组在对照组基础上加用rh-BNP治疗。治疗后对比观察2组患者的临床疗效,测定2组患者治疗前后的血浆B型脑钠肽(BNP)及左心室射血分数(LVEF)水平。结果观察组总有效率为92.0%明显高于对照组的76.0%(P<0.05);治疗后,2组BNP水平均降低,LVEF水平均升高,且观察组波动幅度大于对照组,差异均有统计学意义(P<0.05)。结论运用rh-BNP治疗难治性心力衰竭,可明显减轻心力衰竭的症状,改善患者的心功能,疗效确切。
出处 《临床合理用药杂志》 2016年第34期39-40,共2页 Chinese Journal of Clinical Rational Drug Use
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