期刊文献+

缬沙坦分散片联合不同厂家苯磺酸氨氯地平片治疗高血压的临床疗效及其成本-效果分析 被引量:2

Effect of valsartan dispersible tablets combined with amlodipine besylate tablets from different manufactures in the treatment of hypertension and the analysis of cost-effectiveness
下载PDF
导出
摘要 目的探讨缬沙坦分散片联合不同厂家苯磺酸氨氯地平片治疗高血压的临床疗效及其成本-效果分析。方法选取红炭山矿业有限责任公司龙岩矿区医院2014年10月—2015年4月收治的高血压患者217例,随机分为对照组108例和治疗组109例。对照组患者给予缬沙坦分散片+苯磺酸氨氯地平片(络活喜)治疗;治疗组患者给予缬沙坦分散片+苯磺酸氨氯地平片(安内真)治疗。随访1年,观察比较两组患者的临床疗效、血压情况、服药依从性及不良心脑血管事件发生情况,分析两组患者的成本-效果及其敏感性。结果两组患者治疗总有效率比较,差异无统计学意义(P>0.05)。治疗后,两组患者收缩压、舒张压低于治疗前(P<0.05);治疗前后,两组患者收缩压、舒张压比较,差异无统计学意义(P>0.05)。随访1年,治疗组患者服药依从性优于对照组(P<0.05),均无不良心脑血管事件发生。以治疗组为基准,治疗8周后,治疗组患者用药总费用、C/E值低于对照组;当药品价格下降15%时,治疗组患者成本-效果优于对照组。结论缬沙坦分散片联合安内真治疗高血压安全有效,患者服药依从性好,且成本低,C/E更低。 Objective To discuss the effect of valsartan dispersible tablets combined with amlodipine besylate tablets from different manufactures in the treatment of hypertension and the analysis of cost-effectiveness. Methods A total of 217 cases of patients with hypertension were selected from October 2014 to April 2015 in Longyan Ming Area Hospital,Hongtanshan Mining Limited-liability Company,which were randomly divided into control group( n = 108) and treatment group( n = 109). Control group was given valsartan dispersible tablets combined with amlodipine besylate tablets( An Nei Zhen),treatment group was given valsartan dispersible tablets combined with amlodipine besylate tablets( Luo Huo Xi). Followed-up of 1 year,the clinical effect,blood pressure,compliance of drug administration and the incidence of cardiovascular events were compared between the two groups,analyzed the cost-effectiveness and sensibility. Results No statistically significant difference of total effective treatment was found between the two groups( P > 0. 05). After treatment,the two groups of systolic blood pressure and diastolic blood pressure were lower than prior treatment( P < 0. 05),no statistically significant differences of systolic blood pressure and diastolic blood pressure was found between the two groups before and after treatment( P > 0. 05). Followed-up of 1year,compliance of drug administration of treatment group was better than control group( P < 0. 05),no cardiovascular events was happened. Based on treatment group,after treatment of 8 weeks,treatment group of drug costs,C / E were lower than control group; when prices was fall by 15%,cost-effectiveness of treatment group was better than control group. Conclusion Valsartan dispersible tablets combined with An Nei Zhen have an obviously clinical effect,with higher compliance of drug administration,lower costs and C / E.
作者 胡寿信
出处 《临床合理用药杂志》 2016年第36期13-15,共3页 Chinese Journal of Clinical Rational Drug Use
关键词 高血压 治疗结果 成本-效果 Hypertension Treatment outcome Cost-effectiveness
  • 引文网络
  • 相关文献

参考文献9

二级参考文献120

共引文献5859

同被引文献16

二级引证文献22

;
使用帮助 返回顶部